منابع مشابه
Postmortem Fentanyl Concentrations: A Review
Fentanyl is a potent synthetic narcotic analgesic available through the prescription of various formulations; intravenous injection, transmucosal lollipops and lozenges, as well as transdermal patches. Over the years, fentanyl has been a steadily increasing topic of discussion in the literature with pharmacokinetic studies, postmortem case studies, antemortem case studies, comparison of postmor...
متن کاملPostmortem tissue concentrations of olanzapine.
Twenty-eight cases from 2004-2007 involving olanzapine were analyzed at the San Diego County Medical Examiner's Office. Olanzapine was initially detected by gas chromatography coupled with mass spectrometry (GC-MS), and then confirmed by GC with a nitrogen-phosphorus detector. In cases where olanzapine was detected, concentrations in peripheral blood (PB), central blood (CB), liver, and vitreou...
متن کاملPostmortem femoral blood concentrations of risperidone.
Postmortem femoral blood concentrations of the antipsychotic drug risperidone and the active metabolite 9-hydroxyrisperidone were determined by an achiral LC-MS/MS method in 38 cases. The cause of death was classified as unrelated to risperidone in 30 cases, in which the sum of the concentration of the drug and metabolite ranged from below the limit of quantification to 0.058 mg/kg (median 0.00...
متن کاملSome worlds about postmortem blood atropine concentrations
Atropine is an anticholinergic drug, used in treatment of spasm and pain. Postmortem blood atropine concentrations tend to be regionally dependent. We reported in this work the analytical findings of atropine in the peripheral and heart blood from a case of suspected death. Atropine was determined in both peripheral and heart blood by liquid chromatography with tandem mass spectrometry. Towards...
متن کاملEstimating antemortem drug concentrations from postmortem blood samples: the influence of postmortem redistribution.
AIMS To compare blood drug concentrations during life with postmortem drug concentrations measured from a peripheral site and a central site. METHODS Coroner's cases from October 1990 to July 1997 were reviewed. Six cases had data on both antemortem and postmortem blood drug concentrations. The postmortem to antemortem ratio was compared with the postmortem central to peripheral ratio, using ...
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ژورنال
عنوان ژورنال: Journal of Analytical Toxicology
سال: 2007
ISSN: 0146-4760,1945-2403
DOI: 10.1093/jat/31.4.233